Assessment of Indomethacin , Hyoscine and Piroxycam administration effect before embryo transfer versus routine method on ART outcome.

Effect of administration of Indomethacin , Hyoscine suppository , piroxycam capsule versus routine method before Embryo Transfer on pregnancy rates in ICSI cycles in Vali-e-Asr hospital

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138807252565N3

Enrollment

100

Registered

2012-08-16

Start date

2008-06-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Noninflammatory disorders of female genital tract. Complications of attempted introduction of embryo in embryo transfer

Interventions

Intervention group C:oral l Piroxicam capsule 10 mg 30 minutes before embryo transfer

Intervention 1: Intervention group A:rectal indomethacin 10 mg suppository 30 minutes befror embryo transfer. Intervention 2: Control group: no intervention before embryo transfer ( routine procidure)

Treatment - Drugs

Intervention group A:rectal indomethacin 10 mg suppository 30 minutes befror embryo transfer

Control group: no intervention before embryo transfer ( routine procidure)

Intervention group B:rectal Hyoscine 100 mg suppository 30 minutes before embryo transfer

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 20-35 years, normal response to induction of ovulation Exclusion criteria: history of medical illnesses, endometriosis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate. Timepoint: 4 weeks after ET. Method of measurement: Sonography and blood Test (B-HcG).	—

Secondary

Measure	Time frame
Lower abdominal cramp. Timepoint: After ET. Method of measurement: according to patient complaints.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFedyeh Haghollahi

Vali-e-asr reproductive health research center

fedyeh_hagh@yahoo.com+98 21 6693 9320

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026