Efficacy of topical terbinafine 1% cream in the treatment of facial seborrhoeic dermatitis

Comparsion of efficacy of topical terbinafine 1% cream with topical ketoconazole 2% cream in the treatment of facial seborrhoeic dermatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138807202581N1

Enrollment

105

Registered

2010-10-18

Start date

2010-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seborrhoeic dermatitis. Seborrhoeic dermatitis

Interventions

Intervention 1: topical terbinafine 1% cream, twice a day, for 4 weeks. Intervention 2: Placebo (topical eucerin cream), twice a day, for 4 weeks. Intervention 3: topical ketoconazole 2% cream, twice

Treatment - Drugs

Placebo

topical terbinafine 1% cream, twice a day, for 4 weeks

Placebo (topical eucerin cream), twice a day, for 4 weeks

topical ketoconazole 2% cream, twice a day, for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Presence of seborrhoeic dermatitis Exclusion criteria: application of any treatment that efficient in seborrhoeic dermatitis in last two weeks, presence of AIDS or Parkinson's disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of seborrehic dermatitis. Timepoint: baseline, 4th, 12th week. Method of measurement: Global score.	—

Secondary

Measure	Time frame
Severity of pruritis. Timepoint: Baseline ,4th, 12th weeks. Method of measurement: severity of pruritus is graded from 0 to 3.;Severity of erythem. Timepoint: Baseline, 4th, 12th weeks. Method of measurement: severety of erythema is graded from 0 to 3.;Severety of scaling. Timepoint: baseline, 4th, 12th week. Method of measurement: severity of scaling is graded from 0 to 3.;Side effects. Timepoint: during treatment period. Method of measurement: Erythema or pruritus or burning or contact dermatitis.	—

Measure

Time frame

Severity of pruritis. Timepoint: Baseline ,4th, 12th weeks. Method of measurement: severity of pruritus is graded from 0 to 3.;Severity of erythem. Timepoint: Baseline, 4th, 12th weeks. Method of measurement: severety of erythema is graded from 0 to 3.;Severety of scaling. Timepoint: baseline, 4th, 12th week. Method of measurement: severity of scaling is graded from 0 to 3.;Side effects. Timepoint: during treatment period. Method of measurement: Erythema or pruritus or burning or contact dermatitis.

—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026