Major Depressive Disorder. Depressive episode
Conditions
Interventions
Intervention 1: In behavioral activation group, 16 sessions of BA treatment, for the first month every week two sessions 50 minutes and for the second and third months of the treatment, every week one
Behavior
Treatment - Drugs
In behavioral activation group, 16 sessions of BA treatment, for the first month every week two sessions 50 minutes and for the second and third months of the treatment, every week one session will be
Sertraline 25 mg daily for the first week, 50 mg for the second and third weeks, 75 mg for the fourth and fifth weeks and 100 mg for the sixth week and until the end of the treatment.
Sponsors
Medical university of Kurdistan and Maastricht University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : diagnosis of major depression according to the SCID-I, severity above 19 on the BDI and 13 on the HRSD, age 18-70, written consent to participate with the study. Exclusion criteria : if they have a life time diagnosis of bipolar disorder, organic brain syndrome, psychosis or mental retardation. Additional exclusion criteria are: substantial and imminent suicide risk; a current (e.g., within the past six months) or primary diagnosis of alcohol or drug abuse or dependence or a positive toxicology screen; a primary diagnosis of panic disorder, obsessive-compulsive disorder, psychogenic pain disorder, anorexia, or bulimia. In addition, participants who did not respond favorably within the preceeding year to medication will be excluded. Participants who have unstable medical condition and using any medication that would complicate the administration of antidepressant medication (medication in my study), or have a known allergy to medication in this study will be excluded. Moreover, women who are pregnant or maybe want to be pregnant will be excluded. Lastly, participants have to able to read and understand the questionnaires and interviews used in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment of major depressive disorder. Timepoint: Before intervention, in the middle of Intervention (45 days after starting treatment) and after treament ( after 3 months treatment duration).). Method of measurement: In BA, by BDI-II and In TAU, HRSD is used. | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevention and relapse of major depressive disorder. Timepoint: One year after termination of the treatment. Method of measurement: In BA, by BDI-II and In TAU, HRSD is used. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLatif Moradveisi
Maastricht University
Outcome results
None listed