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Evaluation of adding clonidine to local anesthetic in regional anesthesia for upper extremity surgery

Evaluation of adding clonidine to bupivacaine in supraclavicular block with catheter insertion for upper extremity surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138805312366N1
Enrollment
60
Registered
2010-02-20
Start date
2003-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Fracture of upper limb. Condition 2: Local anaesthetics. Fracture of upper limb Local anaesthetics

Interventions

Intervention 1: Intervention group: adding clonidine 75 mcg to bupivacaine 0.5% in supraclavicular blockade. Intervention 2: Control group: administration of 25 ml bupivacaine 0.5% for supraclavicular
Treatment - Drugs
Intervention group: adding clonidine 75 mcg to bupivacaine 0.5% in supraclavicular blockade
Control group: administration of 25 ml bupivacaine 0.5% for supraclavicular blockade

Sponsors

Iran University of Medical Sciences (IUMS)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients aged 20–60 years (ASA physical status I or II) of both sex, who were candidate for upper extremity (hand, forearm, elbow or arm) surgery, referred to Rasool-Akram hospital. Exclusion criteria: severe uncontrolled underlying diseases (coagulopathy, seizure, cardiac, ...), history of cigarette, opioid, or alcohol abuser, allergy to local anesthetic or clonidine , patient refusal

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sensory and motor blockade in upper extremity. Timepoint: from start of injection to one hour after surgry. Method of measurement: physical exam of sensation and movement in the upper limb.

Secondary

MeasureTime frame
Complications. Timepoint: from start of injection to one hour after surgry. Method of measurement: patient evaluation and observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnad Imani

Iran University of Medical Sciences

farimani@iums.ac.ir+98 21 6651 5758

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026