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The effects of magnesium supplement on muscle strength, muscle function, and inflammatory markers in middle-aged women.

The effects of magnesium supplement on muscle strength, muscle function, and inflammatory markers in middle-aged women.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138805312365N1
Enrollment
80
Registered
2010-01-09
Start date
2009-11-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decrease of muscle strength. Muscle wasting and atrophy, not elsewhere classified

Interventions

Intervention 1: Dietary Magnesium supplement, 250 mg, for 8 weeks. Intervention 2: Placebo, the same tablets as the active drug with the same dose for 8 weeks.
Prevention
Placebo
Dietary Magnesium supplement, 250 mg, for 8 weeks
Placebo, the same tablets as the active drug with the same dose for 8 weeks

Sponsors

Iran Univesity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Age 45 to 55 years old 2. Stopped menstrual cycle for at least 12 month 3. Voluntary participation Exclusion criteria: 1. BMI less than 25 Kg/m2 2. Having one of the following diseases: uncontrolled hypertension, Diabetes, cardiovascular diseases, asthma, Thyroid or parathyroid diseases, renal disorders, liver diseases, bone or rheumatoid disorders, gastrointestinal diseases, and infectious diseases 3. Taking any supplements including minerals, vitamins, and ?-3 fatty acids 4. Receiving hormonal products 5. Cigarette smoking 6. Using one of the following medications: anti-inflammatory drugs (including NSAIDs, steroids, salicylates), aminoglycosides antibiotics, Laxative drug, magnesium-containing drugs 7. compliance less than 70%

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Muscle strength in hand and foot. Timepoint: 8 weeks. Method of measurement: Dynamometer, Handgrip.

Secondary

MeasureTime frame
Inflamentory markers. Timepoint: 8 weeks after intervention. Method of measurement: decline of inflamentory marker.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026