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Effect of Pioglitazone on proteinuria

Evaluating the Effect of Pioglitazone on proteinuria in patients with non diabetic renal disease

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138805222340N1
Enrollment
42
Registered
2010-07-04
Start date
2008-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic renal failure. chronic renal failure

Interventions

15 mg of Pioglitasone, dailly for 4 months.
Treatment - Drugs
15 mg of Pioglitasone, dailly for 4 months

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. proteinuria (>500 mg/ day) for at least 6 months; 2. controlled blood pressure for at least 6 months; 3. age more than 18 years; 4. BMI less than 30; 5. serum creatinin less than 6 mg/dl; 6. no diabetes; 7. not using immunosuppressor agents; 8. no heart failure; 9. no liver disease. Exclusion criteria: 1. changes in doses of drugs which have effect on proteinuria (for example ACEI); 2. incidense of complications attributable to the drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction of proteinuria. Timepoint: Every 2 months. Method of measurement: collection of 24-hour urine protein.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Bahram Pakzad

Isfahan Medical School

pakzad@resident.mui.ac.ir+98 31 1568 3840

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026