pterygium. corneal degeneration
Conditions
Interventions
Intervention 1: Intervention in cases: after excision of pterygium and rotational conjunctival flap,5 mg (0.2ml) of bevacizumab injected subconjunctivally in inferior fornix, and in the first post ope
Treatment - Drugs
Placebo
Intervention in cases: after excision of pterygium and rotational conjunctival flap,5 mg (0.2ml) of bevacizumab injected subconjunctivally in inferior fornix, and in the first post operative week addi
Intervention in controls: after excision of pterygium and rotational conjunctival flap, 0.2 ml of balanced salt solution, injected subconjunctivally in inferior fornix.
Sponsors
Vice-chancellery of Research Affairs of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: the patients with primary pterygium referring to the ophthalmology clinics, affiliated to Shiraz University of Medical Sciences, that want pterygium removal. Exclusion criteria: glaucoma, regurgitation from lacrimal punctum (any indication of nasolacrimal obstruction), patients that seems not coming for follow-up exams during study, not treated diabetic patients, autoimmune diseases, pregnant patients, patients with ocular surface diseases or infections, two headed pterygium, previous limbal surgery, previous pterygial surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of pterygium. Timepoint: 1 month, 3 months, 6 months after operation. Method of measurement: Slit lamp examination and measuring the size of recurrent pterygial tissue on cornea. | — |
Secondary
| Measure | Time frame |
|---|---|
| Healing of the surgical wound. Timepoint: 1 week,1 month. Method of measurement: observing erythema, subconjunctival hemorrhage, corneal epithelial defect, tearing, photophobia of the patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Banifatemi
Shiraz university of medical sciences
Outcome results
None listed