permanent or transient cerebral or retinal ischemic attack. Transient Cerebral Ischaemic attacks and related syndromes-Vascular syndromes of Brain in Cerebrovascular Diseases
Conditions
Interventions
Intervention 1: Aspirin 80 mg TID orally and continuing for 1 year until progression or unacceptable toxicity develops. Intervention 2: Warfarin 5 mg per day orally and adjust it to achieve INR betwee
Treatment - Drugs
Aspirin 80 mg TID orally and continuing for 1 year until progression or unacceptable toxicity develops.
Warfarin 5 mg per day orally and adjust it to achieve INR between 2 and 3 and continue it for 1 year until progression or unacceptable toxicity develops
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: permanent or transient cerebral or retinal ischemia, age more than 18 years old, more than 50 bubbles in echocardiography, presence of atrial septal aneurysm, multiple infarctions in brain CT Exclusion criteria: more than 50% stenosis in colour doppler sonography of neck arteries, thrombosis or ulcerated plaques in neck arteries, other cardiac definite source of stroke
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Permanent or transient cerebral or retinal ischemic attack or death due to any cause. Timepoint: 3 months, 6 months, 9 months and 12 months after intervention. Method of measurement: by phone for recurrence of stroke. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbdolhamid Shariat
Shiraz Neuroscience Research center, Shiraz University of Medical Sciences,
Outcome results
None listed