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Study the effect of pomegranate juice on infertile male sperm

The effect of pomegranate juice consumption on sperm parameters , structure of chromatin of sperm nucleus and sperm apoptosis in infertile men

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138804262168N2
Enrollment
35
Registered
2009-08-07
Start date
2009-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Azoospermia and Oligospermia. Male infertility

Interventions

consumption of pomegranate juice 200cc/day for 10 weeks.
Treatment - Other
consumption of pomegranate juice 200cc/day for 10 weeks

Sponsors

Yazd Research & Clinical Center for Infertility
Lead Sponsor
Research Institute for Islamic & Complementary Medicine
Collaborator

Eligibility

Sex/Gender
Male
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: abnormality in at least one of 3 sperm parameters (count, motility or morphology), age between 20 - 40 years old Exclusion criteria: history of cryptorchidism, varicocele, trauma, azoospermia, any surgery on testis region, specific systemic disease, using systemic disease drug, chronic disease drug or any drug to treat genital system, smoking or opioid abuser.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Improvement of structure of sperm chromatin. Timepoint: 10 weeks after intervention. Method of measurement: CAM3 test & SCD test.;Improvement of sperm parameters. Timepoint: 10 weeks after intervention. Method of measurement: sperm analysis with microscope & macler chamber.;Decrease of sperm apoptosis. Timepoint: 10 weeks after intervention. Method of measurement: TUNEL test.

Secondary

MeasureTime frame
Side effect. Timepoint: during of intervention. Method of measurement: following.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOmid AminiRad

Shaheed Sadoughi University of medical sciences and health services

omid_amini2007@yahoo.com+98 35182440003407

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026