kidney transplant patients with low bone mineral density. Kidney transplant status
Conditions
Interventions
Intervention 1: Pmidronate 90 mg infused in the third week of transplant and third month after the first dose. Intervention 2: Alendronate 70 mg orally administered weekly for 6 months.
Treatment - Drugs
Pmidronate 90 mg infused in the third week of transplant and third month after the first dose
Alendronate 70 mg orally administered weekly for 6 months
Sponsors
Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Kidney transplantation candidates, aged above 20 with low bone mineral density (T-Score 3 mg/dL, Active peptic ulcer disease, Jaw avascular necrosis, Uveitis, History of fracture druring 2 years prior to the study, Achalasia, or delayed esophagus emptying
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density. Timepoint: 6 months. Method of measurement: Dual-energy X-ray absoptiometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Glomerular Filtration Rate. Timepoint: Every month. Method of measurement: Cockcroft-Gault.;Serum Intact Parathormone hormone (iPTH). Timepoint: Every 6 months. Method of measurement: Radioimmunoassay.;Blood level of Cyclosporine. Timepoint: Every month. Method of measurement: Radioimmunoassay. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Javad Shariat Nabavi
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed