Comparison of two-drug regimen of Glucosamine sulfate and Prednisolone with one-drug regimen of Glucosamine sulfate in treatment of knee osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138803242032N1

Enrollment

Registered

2010-11-08

Start date

2009-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoartheritis. Arthrosis, unspecified

Interventions

Intervention 1: glucosamine and prednisolone (case group). Intervention 2: only glucosamine (control group).

Treatment - Drugs

glucosamine and prednisolone (case group)

only glucosamine (control group)

Eligibility

Sex/Gender

All

Age

45 Years to 84 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Chronic pain due to osteoarthritis, Knee cryptation, osteophytes and subchondral sclerosis in radiography, Normal CRP and ESR Exclusion criteria: treatment with NSAIDs, history of trauma, other rheumatologic disorders, diabetes, Hypertension, Knee replacement, immuno depressant

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: week 6 and 12. Method of measurement: WOMAC.	—

Secondary

Measure	Time frame
Movement limitation. Timepoint: week 6 and 12. Method of measurement: WOMAC.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Pourfarzi

Ardabil University of Medical Sciences

f.pourfarzi@arums.ac.ir+98 45 1552 2080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026