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Evaluation of the effect of Gonal F efficacy on sperm analysis parameters in patients with varicocelectomy. A randomized multicentre clinical trial.

Evaluation of the effect of Gonal F efficacy on sperm analysis parameters in patients with varicocelectomy. A randomized multicentre clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138803131267N11
Enrollment
100
Registered
2009-08-29
Start date
2006-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Male infertility

Interventions

Intervention 1: HCG 5000 iu, IM injection, weekly up to 3 month. Intervention 2: HMG 75 iu, IM injection, weekly up to 3 month. Intervention 3: Gonal F, 75 iu, IM injection, 3 times weekly up to 3 mon
Treatment - Drugs
HCG 5000 iu, IM injection, weekly up to 3 month
HMG 75 iu, IM injection, weekly up to 3 month
Gonal F, 75 iu, IM injection, 3 times weekly up to 3 month

Sponsors

Urology and Nephrology Research Center (UNRC), Shahid Beheshti University, M.C.(SBMU), Tehran,
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Inclusion criteria: Men with infertility due to sperm dysfunction, no testis atrophy, nonzero spermatogram test, signing informed consent form. Exclusion criteria: Testis atrophy, zero spermatogram test

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sperm morphology. Timepoint: before and after surgery during 8-10 weeks. Method of measurement: semen analysis.;Sperm quantity in every semen. Timepoint: before and after surgery during 8-10 weeks. Method of measurement: semen analysis.;Sperm motility. Timepoint: before and after surgery during 8-10 weeks. Method of measurement: semen analysis.;Semen amount. Timepoint: before and after surgery during 8-10 weeks. Method of measurement: semen analysis.

Secondary

MeasureTime frame
Pregnancy. Timepoint: every visit. Method of measurement: medical history.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Ali Amirzargar

Urology and Nephrology Research Center (UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.R.

Research @unrc.ir+98 21 2256 7222

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026