menorrhagia. Excessive and frequent menstruation with regular cycle
Conditions
Interventions
Intervention 1: Tranexamic acid, 500mg, Q6h, days1-5 of menstrual cycle. Intervention 2: Medroxyprogestrone asetate, 5 mg, Q12h, days 5-26 menstrual cycle.
Treatment - Drugs
Tranexamic acid, 500mg, Q6h, days1-5 of menstrual cycle.
Medroxyprogestrone asetate, 5 mg, Q12h, days 5-26 menstrual cycle
Sponsors
Research Asisstant of Tarbiat Modares University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 20-45 years old, Regular menses, Heavy menstrual bleeding in several cycles, BMI 19-29 Exclusion criteria: Irregular menses or intra menstrual bleeding, Existence of uterine fibroids>3cm or other pathologic or iatrogenic causes for abnormal bleeding, Any systemic disease affecting menstrual bleeding, Using hormonal drugs (includes OCPs) or other drugs which influence on menstrual bleeding, Having intra uterine device, Pregnancy, Anemia (Hb<11), any therapeutic or preventive regimes for iron deficiency anemia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Menstrual blood loss. Timepoint: one, two and three cycles after intervention. Method of measurement: by using pictorial blood loss assessment chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: before and after intervention. Method of measurement: by using Aberdeen menorrhagia Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Azita Goshtasebi
Tarbiat Modares University
Outcome results
None listed