Effect of oral sucrose and breastfeeding on decreasing pain

The comparison of oral sucrose , breastfeeding and combination method on decreasing the first injective vaccines local pain in infants

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138802101864N1

Enrollment

120

Registered

2010-09-21

Start date

2009-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after first time vaccine injection. Other complications following immunization, not elsewhere classified

Interventions

Control group: no intervention.

Intervention group 3: at first breastfeeding was done and then 0.6 cc/kg sucrose 25% was given.

Intervention group 2: infants were breastfeeded

Intervention 1: Intervention group 1: 0.6 cc/kg sucrose 25%. Intervention 2: Control group: no intervention. Intervention 3: Intervention group 3: at first breastfeeding was done and then 0.6 cc/kg su

duration of breastfeeding was based on the infant’s reluctant.

Prevention

Intervention group 1: 0.6 cc/kg sucrose 25%

Eligibility

Sex/Gender

All

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Infants were under 3 old months. 2. Infants were eligible for receiving first time injective vaccines. 3. Infants had no diseases. 4. Infants had acceptable weight (3-97 percentiles) 5. Infants' parents were satisfied to participate in research. 6. Infants didn't receive sweet food 30 minutes before vaccination. 7. Infants weren't born from diabetic mothers. 8. Infants didn't receive drugs before vaccination especially acetaminophen. 9. Infants were fullterm. 10. Infants weren't breastfeeded or received pacifier at least 30 minutes before vaccination. 11. Infants' mothers did not have any limitations for breastfeeding. 12. Infants' mothers didn't receive drugs. 13. Infants should have vaccination injection pain experiment. 14. Infants sould came to health center with their mothers. Exclusion criteria: 1 - Parents' non-tendency to take part in research process in every stage of study. 2– Breastfeeding from starting infants' monitoring until pain control in 10th minute in control and sucrose groups. 3 – Intensive and long crying which is caused by DPT vaccine, not by pain injection.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: pre-intervention, immediately after intervention, 5th and 10th minutes after intervention. Method of measurement: NIPS (Neonatal Infant Pain Scale).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Hasan Sahebihagh

Tabriz university of Medical Sciences

sahebihagh@tbzmed.ac.ir+98 41 1479 6770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026