Non-ulcer dyspepsia. Dyspepsia
Conditions
Interventions
Intervention 1: Triple therapy (clarithromycin+amoxicillin+omeprazole). Intervention 2: 1g of Nigella sativa seeds powder in capsule + 40mg omeprazole. Intervention 3: 2g of Nigella sativa seeds powde
Treatment - Drugs
Triple therapy (clarithromycin+amoxicillin+omeprazole)
1g of Nigella sativa seeds powder in capsule + 40mg omeprazole
2g of Nigella sativa seeds powder in capsule + 40mg omeprazole
3g of Nigella sativa seeds powder in capsule + 40mg omeprazole
Sponsors
King Faisal University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Patients complaining of dyspeptic symptoms 2) Patients with positive result for H. pylori infection confirmed by both histopathology and rapid urease test (CLO test) Exclusion criteria: 1) the endoscopy showed peptic ulcer, gastric cancer or other gastrointestinal bleeding 2) they had taken proton-pump inhibitors, bismuth or antibiotics in the last 4 weeks before endoscopy 3) pregnant or lactating 4) intolerant to therapeutic regimens
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication of H. pylori. Timepoint: 4 weeks after the end of treatment. Method of measurement: Negative stool antigen by rapid monoclonal immunochromatographic method (ImmunoCard STAT! HpSA, Meridian Bioscience Europe). | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvment in dyspeptic symptoms (epigastric pain and reflux symptoms). Timepoint: 4 weeks after end of teatment. Method of measurement: Questionnaire. | — |
Countries
Saudi Arabia
Contacts
Public ContactDr Muhammad Akram Randhawa
King Faisal University
Outcome results
None listed