Schizophrenia. Schizophrenia, unspecified
Conditions
Interventions
Intervention 1: Prescription of 8 to 10 mg oral risperidone plus three 220 mg oral capsules of zinc sulfate per day for 6 weeks. Intervention 2: Prescription of 8 to 10 mg oral risperidone plus three
Treatment - Drugs
Placebo
Prescription of 8 to 10 mg oral risperidone plus three 220 mg oral capsules of zinc sulfate per day for 6 weeks
Prescription of 8 to 10 mg oral risperidone plus three 220 mg oral capsules of placebo per day for 6 weeks
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: DSM-IV-TR criteria for schizophrenia, PANSS score more than 80, no anti psychotic consumption or seven half-life, the drug was wash out Exclusion criteria: other psychiatric disorders such as substance dependence and physical illnesses, such as liver and renal failure, cardiovascular diseases, allergic and immune system disorders etc.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of symptoms. Timepoint: Baseline and 2nd, 4th, and 6th week. Method of measurement: Positive and Negative Syndrome Scale (PANSS). | — |
Secondary
| Measure | Time frame |
|---|---|
| The speed of risperidone antipsychotic effect. Timepoint: Baseline and 2nd, 4th, and 6th week. Method of measurement: Positive and Negative Syndrome Scale (PANSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehran Zarghami
Mazandaran University of Medical Sciences
Outcome results
None listed