The comparison of topical corticosteroid and Myrtex solution in the treatment of aphthous stomatitis

Randomized comparative clinical trial of topical triamcinolone in orabase (Adcortyle) and Myrtus communis (Myrtex) 5% solution for the treatment of aphthous ulcer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138801201802N1

Enrollment

100

Registered

2009-11-07

Start date

2008-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral aphthous ulcer. Recurrent oral aphthae

Interventions

Intervention 1: Intervention group: Myrtus communis topical solution 10 drops, 5 times/day for 20 seconds on the lesions. Intervention 2: Control group: Topical triamcinolone in orabase, four times/da

Treatment - Drugs

Intervention group: Myrtus communis topical solution 10 drops, 5 times/day for 20 seconds on the lesions

Control group: Topical triamcinolone in orabase, four times/day

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- age range: 18-50 years, 2- size of lesions: 2-4 mm in diameter, 3- number of lesions: 1-5. Exclusion criteria: 1- pregnancy, 2- lactation, 3- present history of any malignancy, 4- Behcet's Syndrome

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain relief. Timepoint: one week after treatment. Method of measurement: history of the patients.;Healing of the aphthous ulcer. Timepoint: one week after treatment. Method of measurement: clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Farrokh Rad

Kurdistan University of Medical Sciences

dr_farokh.rad@muk.ac.ir+98 87 1328 5913

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026