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Post operative pain management

Multimodal Preincisional Early Premedication to Prevent Pain After Cholecystectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138712291772N2
Enrollment
60
Registered
2010-05-31
Start date
2009-05-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Cholecystitis and cholelithiasis. Condition 2: opioid consumption. Calculus of gallbladder with other cholecystitis and Other cholelithiasis

Interventions

Intervention 1: Control group: instead of Diclofenac, Clonidine and Ketamine they received placebo before the operation, but the surgical site infiltrated with Bupivacaine 0.25% before incision. Inter
Placebo
Treatment - Drugs
Control group: instead of Diclofenac, Clonidine and Ketamine they received placebo before the operation, but the surgical site infiltrated with Bupivacaine 0.25% before incision
Intervention group received Diclofenac suppository 100 mg, Clonidine 0.2 mg half an hour before surgery and Ketamine 50 mg IV after induction of anesthesia. Site of Incision were infiltrated before th

Sponsors

Tabriz medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion: age from 20 to 60 people who are going to have open chlecyctectomy; Exclusion criteria : Coagulopathty, Refuse to participate, Addiction, hypochonderiasis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 2, 4, 6, 12, 24, and 48 hours after operation. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Opioid consumption. Timepoint: 2, 4, 6, 12, 24, and 48 hours after operation. Method of measurement: Total dose.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDawood Aghamohammadi

Anesthesiology Dept

aghamohammadid@tbzmed.ac.ir+98 41 1381 8940

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026