Vaccination of cancer patients for preventing cancer development

Vaccination of diffuse B cell lymphoma patients by use of tumor antigens and autologous dendritic cells complex

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT138712071715N1

Enrollment

Registered

2009-05-31

Start date

2009-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma. B-cell lymphoma, unspecified

Interventions

After antigen priming, subcutaneous injection of median of 6.5 × 1000000 (0.5 ml) dendritic cells, close to inguinal lymph nodes, twice a day.

After antigen priming, subcutaneous injection of median of 6.5 × 1000000 (0.5 ml) dendritic cells, close to inguinal lymph nodes, twice a day

Eligibility

Sex/Gender

All

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Presence of diffuse b cell lymphoma Exclusion criteria: Presence o any other kind of cancer except for lymphoma

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The number of TCD4. Timepoint: one week after injection. Method of measurement: Flocytometry.;The number of TCD8. Timepoint: one week after injection. Method of measurement: Flocytometry.	—

Secondary

Measure	Time frame
Interleukin 2. Timepoint: 7 to 14 days after injection. Method of measurement: eliza.;Interleukin 4. Timepoint: 7 to 14 days after injection. Method of measurement: ELIZA method.;Interleukin 10. Timepoint: 7 to 14 days after injection. Method of measurement: ELIZA method.;Interleukin 17. Timepoint: 7 to 14 days after injection. Method of measurement: ELIZA method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMotahareh Kheradmand

Mazandaran University of Medical Sciences

elhamkheradmand2003@yahoo.comkheradmand@mazums.ac.ir+98 15132612458

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026