Chronic Renal Failure. Diseases of the genitourinary system
Conditions
Interventions
Simvastatin, 20 mg daily, for 4 months.
Treatment - Drugs
Simvastatin, 20 mg daily, for 4 months
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 15-70 years, presence of chronic renal failure, LDL more than 100 Exclusion criteria: Immune deficiency, receiving corticosteroid, NSAID or other drugs that affect on lipid profile, LDL>100, presence of malignancy or connective tissue disorder, hypersensitivity to Simvastatin
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| IL6. Timepoint: Baseline and 4 months after intervention. Method of measurement: Direct Serum Measurement (ELISA).;Lipid profile (TG, CHOLESETROL, HDL, LDL). Timepoint: Baseline and 4 months after intervention. Method of measurement: Direct measurement of TG, Cholestrol, and HDL, and LDL by formula.;HS-CRP. Timepoint: Baseline and 4 months after intervention. Method of measurement: Direct Serum Measurement (ELISA). | — |
Primary
| Measure | Time frame |
|---|---|
| Renal Function Test. Timepoint: Baseline and 4 months after intervention. Method of measurement: GFR, BUN, Creatinine. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mahmood Akhzari
Shiraz University of Medical Sciences
Outcome results
None listed