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The effect of intravenous acetaminophen in reducing Post-operative opioid requirements after maxillofacial surgery.

A Clinical trial of paracetamole administration after maxillofacial surgery in Post-operative opioid requirements.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138711221674N1
Enrollment
100
Registered
2012-01-28
Start date
2011-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maxillofacial Surgery( correction after injury).

Interventions

Intervention 1: Equal to 50 divided randomly into two groups, so that odd numbers - received paracetamol (Group A) and even numbers - receiving placebo (group II) are divided. Complete questionnaires
Treatment - Drugs
Placebo
Equal to 50 divided randomly into two groups, so that odd numbers - received paracetamol (Group A) and even numbers - receiving placebo (group II) are divided. Complete questionnaires in the surgery's
After transfer the patient to the recovery room and extubation of trachea, and eventually the patient returned to full consciousness, with relation to the patient's pain is measured and recorded. Plac

Sponsors

Vice chancellor for research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 15 to 45-year-old patients; and class I patients (ASA) Exclusion criteria: The patients out of age range of 15 to 45 years; patients other than class I (ASA)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patient's hemodynamic data are evaluated in recovery room. Timepoint: 12 hours after injection of paracetamol. Method of measurement: Blood pressure and heart rate were evaluated by digital monitoring devices.;Pain of patients were measured. Timepoint: first , second, fourth, sixth, eighth, tenth, twelfth hour. Method of measurement: visual analog scale (100-mm).

Secondary

MeasureTime frame
Patient's satisfaction. Timepoint: 12 hrs. and 24 hrs. after injection. Method of measurement: questionnaire which evaluated as poor(0), moderate(1), good(2), excellent(3).;Medication's side effects such as nausea, vomiting, gastrointestinal upset, allergic reactions, urinary retention, diarrhea, constipation was noted. Timepoint: 12 hrs. and 24 hrs. after injection. Method of measurement: Through a questionnaire that contains information about the drug side effects.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Eftekharian

Shiraz University of Medical Sciences

eftekharhr@sums.ac.ir0098

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026