The Effect of Ultra-Low Dose of Naloxone Added to Lidocaine-Fentanyl Mixture on Axillary Brachial Plexus Blockade

Phase 2 Study of Assessing the Effect of Ultra-Low-Dose Naloxone on Accentuating the Effect of Fentanyl on Enhancing the Local Anesthetic Characteristic of Lidocaine

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT138711211666N1

Enrollment

Registered

2009-02-12

Start date

2009-02-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Fracture of distal of radius. Condition 2: Local Anesthesia. Fracture of lower end of radius Local anaesthetics

Interventions

Intervention 1: 34ml 1.5% lidocaine solution containing 100 ng naloxone. Intervention 2: 34ml 1.5% lidocaine alone. Intervention 3: 34ml 1.5%lidocaine solution containing 100 microgram fentanyl. Inter

34ml 1.5% lidocaine solution containing 100 ng naloxone

34ml 1.5% lidocaine alone

34ml 1.5%lidocaine solution containing 100 microgram fentanyl

34ml 1.5% lidocaine solution containing 100 microgram fentanyl & 100 ng naloxone

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Distal Radius Fracture; Exclusion Criteria: Diabetes mellitus, Addiction, Recent analgesic or narcotic medication.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Block Time. Timepoint: every 15 minutes. Method of measurement: Pinprick test.	—

Secondary

Measure	Time frame
Post operative pain. Timepoint: every 4 hrs. Method of measurement: VAS (visual analog scale).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Movafegh

Anesthesiology Dep, Tehran University of Medical Sciences

movafegh@sina.tums.ac.ir, ali@movafegh.com+98 21 8490 2372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026