Peptic ulcer, bleeding. Peptic ulcer, site unspecified
Conditions
Interventions
Intervention 1: All patients who admit in odd days will take oral omeprazole (40 mg po BID ) and then 20 mg omeprazole daily up to 14 days.All patient will evaluate endoscopically and endoscopic in
Treatment - Drugs
All patients who admit in odd days will take oral omeprazole (40 mg po BID ) and then 20 mg omeprazole daily up to 14 days.All patient will evaluate endoscopically and endoscopic intervention would
patients who will admit in even days will recieve pantoprazole ( 8 mg / hour ) for 72 or 48 hour and then take omeprazole 20 mg daily up to 14 days .
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA ;All patient who admite in hospital due to GI bleeding and have high risk ulcer in endoscopic evaluation. EXCLUSION CRITERIA ;Any patient who find to have esophageal varices ,bleeding tendency ,GI cancer ,uremia or Mallory Weiss tear.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrent bleeding. Timepoint: daily up to discharge and after 14 days. Method of measurement: hypotension,tachucardia ,Hb drop ,hematemesis after stabilization and recurrence of melena after normal stool.;Surgery. Timepoint: daily up to discharge and after 14 days. Method of measurement: daily up to discharge and phone call after 2 weeks.;Mortality (All cause ). Timepoint: daily up to discharge. Method of measurement: daily up to discharge and phone call after 2 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion. Timepoint: during discharge. Method of measurement: number of transfused blood packed cells.;Hospital stay. Timepoint: daily. Method of measurement: assess during discharge. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Alireza Hashemi
Shiraz University of Medical Sciences
Outcome results
None listed