Saffron and decrease of sexual dysfunction induced by fluoxetin

The effect of Crocus Sativus L. on sexual dysfunction induced by Selective Seretonin Reuptake Inhibitors in male: a clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT138711121556N3

Enrollment

Registered

2009-02-11

Start date

2009-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction. Lack or loss of sexual desire

Interventions

Intervention 1: Cap Saffron 15 mg twice per day as intervention group. Intervention 2: Cap Placebo twice per day as control group.

Placebo

Cap Saffron 15 mg twice per day as intervention group

Cap Placebo twice per day as control group

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: at least 4 weeks usage of fluoxetin before study, do not use any psychotherapeutics except Selective Seretonin Reuptake Inhibitors, lack of chronic and organic disorders including cardiovascular diseases, informed consent. Exclusion Criteria: substance dependence, organic disorders, other psychiatric comorbidity including biploar disorder, use of psychotropic drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Score of international index of Erectile Function. Timepoint: every two weeks. Method of measurement: use of international index of Erectile Function.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026