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The effect of adding dexamethasone to intracuff lidocaine 2% on decreasing the respiratory complications after general anesthesia: a randomized, double blind, clinical trial

The effect of adding dexamethasone to intracuff lidocaine 2% on decreasing the respiratory complications after general anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138711111617N1
Enrollment
208
Registered
2010-06-14
Start date
2009-06-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cough. Whooping cough, unspecified

Interventions

Dexamethasone, Intracuff until there was no air leak at 25 CmH2o airway pressure
Intervention 1: control group: air, Intracuff until there was no air leak at 25 CmH2o airway pressure. Intervention 2: Lidocaine 2%, Intracuff until there was no air leak at 25 CmH2o airway pressure.
Treatment - Drugs
control group: air, Intracuff until there was no air leak at 25 CmH2o airway pressure
Lidocaine 2%, Intracuff until there was no air leak at 25 CmH2o airway pressure
Lidocaine2%+dexamethasone, Intracuff until there was no air leak at 25 CmH2o airway pressure

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA class I-II, candidate for elective surgery under general anesthesia with tracheal intubation Exclusion criteria: head and neck surgery, respiratory tract infection, asthma, nasogastric tube, increase intracranial or intraoccular pressure, denial of patients

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cough. Timepoint: At the baseline and one hour and 24 hours later. Method of measurement: observation.;Bucking. Timepoint: At the baseline and one hour and 24 hours later. Method of measurement: observation.;Laryngospasm. Timepoint: At the baseline and one hour and 24 hours later. Method of measurement: observation.

Secondary

MeasureTime frame
Pharyngeal pain. Timepoint: At the baseline and again 24 hours later. Method of measurement: visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Johari

Imam Reza Hospital

mchoobsaz@kums.ac.ir+98 83 1724 6708

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026