Autism. Childhood autism
Conditions
Interventions
Intervention 1: Intervention: Risperidone + Celecoxib 300 mg/day. Intervention 2: Control: Risperidone + placebo.
Treatment - Drugs
Placebo
Intervention: Risperidone + Celecoxib 300 mg/day
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 11 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Ages 3 to 11 years, clinical diagnosis of autism (the diagnosis of autism based on semi structured interview with the parent), lack of use of psychotropic drugs at least two weeks before trial. Exclusion Criteria: Previously received neuroleptics or any psychotropic drug treatment 6 months prior to recruitment or having significant active medical problem; Children with severe or profound mental retardation in whom a definitive diagnosis of autism could not be made; Any diagnosis of psychiatric disorder in Axis I and II; Any organic disorder.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Aberrant Behavior Checklist (ABC). Timepoint: every two weeks. Method of measurement: The Aberrant Behavior Checklist (ABC).;Childhood Autism Rating Scale. Timepoint: every two weeks. Method of measurement: Childhood Autism Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed