Cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: First group: fluconazol 200mg/daily for six weeks. Intervention 2: Second group: fluconazol 400mg/daily for six weeks.
Treatment - Drugs
First group: fluconazol 200mg/daily for six weeks
Second group: fluconazol 400mg/daily for six weeks
Sponsors
Shiraz University of Medical Scienses
Eligibility
Sex/Gender
All
Age
12 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age over 12 years, positive PCR for leishmanisis and no treatment in two months ago, duration of disease is lower than 4 months. Exclusion criteria: pregnancy, breast feeding, possibility of pregnancy in future, number of lesion over ten, history of liver disease and high BUN or Cr.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reepithelialization. Timepoint: every two week. Method of measurement: observation.;Size of lesion. Timepoint: every two week. Method of measurement: with ruler.;Induration of lesion. Timepoint: every two week. Method of measurement: physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rising of liver enzyme, BUN and Cr. Timepoint: every two week. Method of measurement: Blood sample and laboratory measurment.;Nausea and vomitting. Timepoint: every two week. Method of measurement: History. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHayati Fariborz MD
Shiraz University of Medical Sciences
Outcome results
None listed