Effect of hydroxychloroquine on symptoms of patients with knee osteoarthritis

Effect of hydroxychloroquine on symptoms of patients with knee osteoarthritis who will attend to rheumatology clinic of Imam Reza Hospital of Mashhad Mashhad

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138709121479N1

Enrollment

Registered

2008-12-23

Start date

2008-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis. Primary gonarthrosis, bilateral, Other primary gonarthrosis

Interventions

None listed

Eligibility

Sex/Gender

All

Age

45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) Knee osteoarthritis according to ACR criteria 2) Knee osteoarthritis grade I & II (Kellgren and Lawrence grades) 3) Age 45-65 years 4) Ability to read and write Exclusion criteria: 1) Secondary osteoarthritis 2) Osteoarthritis grade> II 3) History of knee arthroscopy during the last 6 months 4) History of intra-articular corticosteroid injection during the last 6 months 5) History of hypersensitivity to antimalarial drugs 6) Any eye problem

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Knee osteoarthritis symptpms. Timepoint: every month for 6 months. Method of measurement: WOMAC Index.	—

Secondary

Measure	Time frame
Joint cartilage thickness. Timepoint: At the begining and six months after intervention. Method of measurement: Joint space meaturement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammadhassan Jokar

Imam Reza Hospital, Mashhad University for Medical Sciences

jokarmh@mums.ac.ir+98 51 1859 8818

Outcome results