Pain after periodontal surgery. Chronic periodontitis
Conditions
Interventions
Intervention 1: Celecoxib, 200 mg capsule, one hour before surgery and the second dose, 12 hours after the first dose. Intervention 2: Placebo, capsule first dose, one hour before surgery and the seco
Treatment - Drugs
Celecoxib, 200 mg capsule, one hour before surgery and the second dose, 12 hours after the first dose
Placebo, capsule first dose, one hour before surgery and the second dose, 8 hours after the first dose
Prednisolone tablet, 10 mg one hour before surgery and the second dose, 8 hours after the first dose
Sponsors
Vice-chancellor for Research, Faculty of Dentistry, Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Otherwise healthy individuals having moderate to severe chronic periodontitis and Being a candidate for mucoperiosteal flap with minor osseous surgery in at least 3 quadrants of dentition Exclusion criteria: Diabetes mellitus, uncontrolled hypertension, gastric ulcer, pregnancy or breast feeding, allergy to drugs consumed in the study, high risk for Infective Endocarditis
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: From the first hour after surgery for 8 hours, every hour, and at the morning, noon and night of the day after surgery ( 11 time points). Method of measurement: visul analoge scale and, five-point verbal rating scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment of periodontal disease. Timepoint: One week after surgery. Method of measurement: Examination by an expert surgeon. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNastaran Mirfarhadi
Guilan University of Medical sciences, School of Dentistry, Research Center
Outcome results
None listed