Condition 1: low birth weight. Condition 2: hyperbilirubinemia. Other low birth weight Neonatal jaundice associated with preterm delivery
Conditions
Interventions
Intervention 1: in cases: clofibrate 100 mg/kg once time/ day. Intervention 2: in controls: distilled water once time/ day.
Treatment - Drugs
Placebo
in cases: clofibrate 100 mg/kg once time/ day
in controls: distilled water once time/ day
Sponsors
mashhad university of medical science
Eligibility
Sex/Gender
All
Age
2 Years to 28 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:All neonates with birth weight less than 2500gr who have icter. Exclusion criteria: the presence of a hemolytic, infection, congenital anomaly or metabolic disorder and undergoing mechanical ventilation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreasing of serum bilirubin. Timepoint: befor intervention and 12,24,48,72 and 96 hours after intervention. Method of measurement: measurment of serum bilirubin (diazo method). | — |
Secondary
| Measure | Time frame |
|---|---|
| Tereatment of jaundice of neonate. Timepoint: befor intervention and 24,48,72 and 96 hours after intervention. Method of measurement: decreasing of jaundice and bilirubin level in blood serum. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Ashraf mohammadzadeh
Neonatal Research Center
Outcome results
None listed