Prophylactic effect of clofibrate in very low birth weight neonates' hyperbilirubinemia

Prophylactic effect of colofibrate in very low birth weight neonates' hyperbilirubinemia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138706311162N5

Enrollment

Registered

2008-10-28

Start date

2006-04-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperbilirubinemia in low birth weight neonates.

Interventions

Intervention 1: 100 mg/kilogram clofibrate. Intervention 2: The same volume of strile water as Placebo.

100 mg/kilogram clofibrate

The same volume of strile water as Placebo

Eligibility

Sex/Gender

All

Age

1 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion:low birth weight neonates who were admitted to NICU of Emamreza Hospital.These neonates were healthy, breastfed with birth weight equal or less than 2500 grams. exclusion: Babies with hemolysis, infections, congenital anomalies and metabolic diseases were excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum Bilirubin. Timepoint: before intervention, 24, 48, 72, and 96 hours after intervention. Method of measurement: measurment of serum bilirubin (diazo method).	—

Secondary

Measure	Time frame
Incidence of jaundice in low birth weight neonates. Timepoint: before intervention,24,48,72 and 96 hours after intervention. Method of measurement: Physical examination (yes/no).	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026