Improvement of refractive outcomes in myopic regression after Laser in Situ Keratomileusis using timolol: A randomised clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138706271258N1

Enrollment

100

Registered

2009-12-05

Start date

2009-04-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regression after lasik surgery. Myopia

Interventions

Intervention 1: Timolol drop

every 12 hours for each eye

for 6 months. Intervention 2: Artificial tear drop

for 6 months.

Treatment - Drugs

Placebo

Timolol drop

for 6 months

Artificial tear drop

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Having undergone Lasik surgery, both eyes have had at least -0.5 D return Exclusion criteria: Incidence of complications during the surgery, presence of background diseases such as glaucoma, heart failure, digestive problems, cancer, favism, myasthenia gravis, or asthma

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Refractive error. Timepoint: before intervention; 2 months and 6 months after intervention. Method of measurement: auto refractive, objective refractive, subjective refractive.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohmmd Mansouri

Tehran University of Medical Sciences

mmansouri@student.tums.ac.ir+98 21 2205 6391

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026