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Effect of Clofibrate in Jaundiced Term newborns

Effect of Clofibrate in Jaundiced term Newborns

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138706261162N4
Enrollment
60
Registered
2008-10-28
Start date
2002-11-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Jaundice in healthy, term newborn.

Interventions

Intervention 1: Phototherapy + clofibrate(100 mg/kg, single dose). Intervention 2: Phototherapy.
Phototherapy + clofibrate(100 mg/kg, single dose)
Phototherapy

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 19 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: healthy jaundiced, breastfed neonates, delivered between 38th and 41st week of gestational age after an uncomplicated pregnancy and serum bilirubin(TSB) between 17 and 29.9 mg/dl ,age less than 28 days exclusion criteria: congenital anomaly, hemolytic disease (Rh or ABO incompatibility and a positive coombs' test), infection (congenital or acquired), dehydration, G6PD deficiency and conjugated bilirubin>2.0 mg/dl or exceeding 15% of total serum bilirubin,age more than 28 days

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum bilirubine. Timepoint: Before intervention-12,24 and 48 after intervention. Method of measurement: Measuring serum bilirobin(diazo method).

Secondary

MeasureTime frame
Duration of need to phototrapy. Timepoint: daily. Method of measurement: Duration of phototherapy (days).

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026