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The treatment of Acne Vulgaris

Comparison of theraputic effects of topical Azithromycin , Erythromycin and Clindamycin for the treatment of acne vulgaris

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138706231245N1
Enrollment
96
Registered
2009-04-19
Start date
2006-04-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris. Acne vulgaris

Interventions

Intervention 1: Topical Azithromycin, 2% alcohol solution, two times daily on the clean skin for 3 months. Intervention 2: Topical Erythromycin and Clindamycin, 2% alcohol solution, two times daily on
Treatment - Drugs
Topical Azithromycin, 2% alcohol solution, two times daily on the clean skin for 3 months
Topical Erythromycin and Clindamycin, 2% alcohol solution, two times daily on the clean skin for 3 months

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Presence of mild to moderate Acne Vulgaris (up to 10 comedons, papular and/or pustular lesions). Exclusion criteria: pregnant and breast feeding women, children younger than 10 years old, severe cases of acne (existence of nodules and cysts), receiving anti acne during four weeks prior to study, taking acne creating drugs such as oral or local steroids, vitamin B12, anticonvulsive drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Inflammatory and noninflammatory lesions. Timepoint: Baseline and after 2,4,8, and 12 weeks. Method of measurement: counting lesions using manual lens.

Secondary

MeasureTime frame
Reduction of lesions inflammatory and noninflammatory. Timepoint: Baseline and after 2, 4, 6, and 8 weeks. Method of measurement: ASI formula and total count rate.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRavanbakhsh Esmaeeli

Mazandaran University of Medical Sciences(Vice-chacellor for Research)

Esmaeeli2003@yahoo.com+98 15 1325 7230

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026