Diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Aloe vera jell powder 150 mg in capsule two times a day for two months. Intervention 2: Aloe vera jell powder 300 mg in capsule two times a day for two months. Intervention 3: placebo
Treatment - Drugs
Placebo
Aloe vera jell powder 150 mg in capsule two times a day for two months
Aloe vera jell powder 300 mg in capsule two times a day for two months
placebo 150 mg in capsule two times a day for two months
placebo 300 mg in capsule two times a day for two months
Sponsors
Jahad Daneshgahi
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 40 to 60 years, confirmed type II diabetes at least for two years with fasting blood glucose above 150-250 mg/dl taking Metformin or Glibenclamid, HbA1c 7.5-10%, singing the written informed consent. Exclusion criteria: insulin therapy, infectious diseases, severe kidney, liver, heart, or pulmonary disease, hypersensitivity to any drug, foot ulcer or gangrene, major depressive disorders, previous myocardial infarction, active cancer or previous cancer during the last 5 years, alcohol consumption, cigarette smoking, pregnancy, and breast feeding.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose. Timepoint: Baseline and after one and two months. Method of measurement: Glucose oxidase method.;Glycosylated hemoglobin. Timepoint: Baseline and after two months. Method of measurement: HPLC method. | — |
Secondary
| Measure | Time frame |
|---|---|
| SGOT. Timepoint: Baseline and after two months. Method of measurement: SGOT level in fasting blood sample by DGKG enzymatic method.;SGPT. Timepoint: Baseline and after two months. Method of measurement: SGPT level in fasting blood sample by DGKG enzymatic method.;Creatinin. Timepoint: Baseline and after two months. Method of measurement: The fasting blood Creatinin level by JAPH enzymatic method.;Cholesterol. Timepoint: Baseline and after two months. Method of measurement: Fasting blood Cholesterol level by enzymatic oxidase method.;LDL. Timepoint: Baseline and after two months. Method of measurement: Fasting blood LDL level by CDC designated comparison method.;HDL. Timepoint: Baseline and after two months. Method of measurement: Fasting blood HDL level by enzymatic oxidase method.;Triglyceride. Timepoint: Baseline and after two months. Method of measurement: Fasting blood Triglyceride level by enzymatic oxidase method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFallah Huseini Hassan
Institute of Medicinal Plants, ACECR
Outcome results
None listed