Ovarian Hyperstimulation Syndrome.
Conditions
Interventions
Intervention 1: In coasting group, exogenous gonadotropins will be withheld to allow E2 to decrease while GnRH-a will be maintained. Then 10,000 Unit hCG will be administrated and oocyte retrieval wil
Prevention
In coasting group, exogenous gonadotropins will be withheld to allow E2 to decrease while GnRH-a will be maintained. Then 10,000 Unit hCG will be administrated and oocyte retrieval will be performed 3
In Cabergoline group, hCG will be administered and they receive 0.5 mg per day cabergoline orally from the day of hCG for 8 days. Luteal phase will be supported by administration of progesterone in oi
Sponsors
Research and Clinical Center for Infertility, Yazd Shahid Sadoughi University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with In Vitro Fertilization (IVF)/Intra Cytoplasmic Sperm Injection (ICSI) cycles who are at risk of developing OHSS. The definition of risk is: the presence of pre- ovulatory follicles = 20 in both ovaries.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Severe OHSS. Timepoint: 2 weeks. Method of measurement: Clinical Management. | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation Rate. Timepoint: 2 weeks. Method of measurement: Number of gestational sacs per embryo transferred.;Clinical Pregnancy Rate. Timepoint: 2 weeks. Method of measurement: Embryonic cardiac activity observed by ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactabbas aflatoonian
Research and Clinical Center for Infertility?Yazd Shahid Sadoughi University of Medical Sciences
Outcome results
None listed