Comparison between the oral and vaginal Misoprostol effects on Pregnancy Termination in Second

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138706061106N1

Enrollment

Registered

2008-09-27

Start date

2006-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pregnancy termination in Second Trimester.

Interventions

Intervention 1: Intervention:vaginal misoprostol. Intervention 2: Control: oral misoprostol.

Intervention:vaginal misoprostol

Control: oral misoprostol

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria : Pregnant women in( 14- 28 week) were candidate in termination because of missed abortion ,fetal abnormality ,fetal death and premature rupture of membrane. Exclusion criteria :Uncontrolled seizure, asthma,glucohema,hypertension ,COPD,mitral stenosis,inflammatory intestinal disease,history of allergy to PG E1.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
PREGNANCY TERMINATION. Timepoint: begining of study -every 6 hours up to 48 hours. Method of measurement: dilatation of cervix-contraction and hemorrhage.	—

Secondary

Measure	Time frame
Gastrointestinal disorders. Timepoint: every one hours until the last dosage. Method of measurement: Clinical examination.;Fever. Timepoint: every one hours until the last dosage. Method of measurement: vital sign.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Behrashi

kashan university of medical sciences

dr-behrashi2006@yahoo.com+98 36 1446 0180

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026