Mania episode. Mania episode
Conditions
Interventions
Intervention 1: Intervension: Risperidone tablet(4 mg/day) combined with tamoxifen tablet (80 mg/day) + lithium tablet 1800mg/day as intervention group for 6 weeks. Intervention 2: Control group: Risp
Treatment - Drugs
Intervension: Risperidone tablet(4 mg/day) combined with tamoxifen tablet (80 mg/day) + lithium tablet 1800mg/day as intervention group for 6 weeks
Control group: Risperidone tablet (4 mg/day) combined with placebo tablet + lithium tablet 1800mg/day as control group for 6 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients aged between 18 and 49 wioll be eligible to participate, as they meet the DSM-IV criteria for a current manic episode, on the basis of a clinical interview by two academician psychiatrists. In addition, a score of at least 20 points on the YoungMania Rating Scale will be required representing at least a moderate-to-severe mania. Exclusion criteria: Other diagnosis in Axix 1, substance dependence, severe medical problems and lactating and pregnant women.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Young Mania Rating Scale. Timepoint: evey two weeks from the begining of trial till week 8. Method of measurement: by Young Mania Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed