Autism. ?????? ??????
Conditions
Interventions
Intervention 1: Risperidone + memantine 20mg/day. Intervention 2: Control: Risperidone + placebo.
Treatment - Drugs
Risperidone + memantine 20mg/day
Sponsors
Tehran University of Medical Sciences,
Eligibility
Sex/Gender
All
Age
3 Years to 11 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Ages 3 to 11 years, clinical diagnosis of autism, lack of use of psychotropic drugs at least two weeks before trial. Exclusion Criteria: having significant active medical problem; Previously received neuroleptics or any psychotropic drug treatment 6 months prior to recruitment; Any diagnosis of psychiatric disorder in Axis I and II; Children with severe or profound mental retardation in whom a definitive diagnosis of autism could not be made
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Aberrant Behavior Checklist (ABC). Timepoint: weeks 2-4-6-8-10 after begining of trial. Method of measurement: The Aberrant Behavior Checklist (ABC). | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety. Timepoint: weeks 2,4,6.8,10 after begining of trial. Method of measurement: side effects checklist. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed