Temporomandibular osteoarthritis.
Conditions
Interventions
Product Name: Nanofat
Pharmaceutical Form: Emulsion for injection
INN or Proposed INN: Nanofat
Other descriptive name: Nanofat
Concentration unit: U/ml unit(s)/millilitre
Concentration type: up to
Con
Sponsors
University of Tartu Institute of Dentistry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Estonian speaking patients, aged between 18-64 years. Patients who are able to give consent. Patients who are diagnosed with temporomandibular osteoarthritis and who have received conservative treatment before, which has not given desireable results. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 14 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Pregnancy. Severe chronic illnesses. Patients, who have received surgical TMJ intervention in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To find out if nanofat injections into the temporomandibular joint reduces symptoms which are caused by temporomandibular osteoarthritis.;Secondary Objective: To assess changes in temporomandibular joint up to 12 months based on MRI scans. ;Primary end point(s): N/A;Timepoint(s) of evaluation of this end point: N/A | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): N/A;Timepoint(s) of evaluation of this end point: N/A | — |
Countries
Estonia
Contacts
Public ContactStomatology Clinic
Tartu University Hospital
Outcome results
None listed