Pain after burns MedDRA version: 20.0 Level: LLT Classification code 10006634 Term: Burn System Organ Class: 100000004863
Conditions
Interventions
Trade Name: Penthrox
Pharmaceutical Form:
Sponsors
Rigshospitalet
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Burns with need for change of wound dressing. Age at least 18 years, able to provide informed consent. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 25 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 5
Exclusion criteria
Exclusion criteria: Renal failure (GFR below 60 ml/min) Liver failure Liver toxicity after exposure to halogenated inhalational anaesthetics Genetic predisposition for malignant hyperthermia. Current treatment with isoniazide, gentamicine, tetracycline, colistien or amphotericine B.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To assess pain relief of methoxyflurane in patients with burns undergoing change of wound dressing;Secondary Objective: To assess side effects of methoxyflurane;Primary end point(s): Pain intensity ;Timepoint(s) of evaluation of this end point: During change of wound dressing | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Side effects nausea, vomiting, headache, coughing;Timepoint(s) of evaluation of this end point: After change of wound dressing | — |
Countries
Denmark
Contacts
Public ContactDept Anaesthesia
Rigshospitalet
Outcome results
None listed