postoperative pain
Conditions
Interventions
Trade Name: Arcoxia 60 mg filmtabletta
Pharmaceutical Form:
INN or Proposed INN: etoricoxib
CAS Number: 202409-33-4
Other descriptive name: ETORICOXIB
Concentration unit: mg milligram(s)
Concentratio
Sponsors
Semmelweis Egyetem Fogorvostudományi Kar Arc- Állcsont- Szájsebészeti és Fogászati Klinika, Budapest
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: female and male patients aged between 18 and 30, without any current medical conditions or existing in the medical history. class I and II, A and B positioned (Pell & Gregory) wisdom teeth will be removed (with the exception of Class II B- due to the more invasive surgery a longer healing period is suspected) Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 75 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Patients will be excluded if the following conditions exist: - patients under medication (we would like to avoid the interactions) - patients who have taken any type of a painkiller during the week prior to the surgery - smokers (longer healing period is suspected) - pregnancy - patients in breast feeding period - patients with allergy for the examined medicaments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: to compare the preventive painkiller efficacy of the examined substances (celecoxib and etoricoxib);Secondary Objective: to evaluate the necessity of the preventive usage of selective COX-2 inhibitors prior to M3M surgery;Primary end point(s): The volume of the postoperative pain will be estimated by the patients on a Visual Analog Scale where 0 means no pain et all ad 10 equals the unbearable pain;Timepoint(s) of evaluation of this end point: pain should be registered in the first 8 hours after the surgery and on the next day of the intervention in three different timepoints (09:00, 15:00 és 21:00) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): the rate of the discomfort will be registered on a verbal rating scale (VRS-4);Timepoint(s) of evaluation of this end point: the discomfort should be registered in the first 8 hours after the surgery and on the next day of the intervention in three different timepoints (09:00, 15:00 és 21:00) | — |
Countries
Hungary
Contacts
Public ContactSemmelweis Egyetem Fogorvostudomány
Semmelweis Egyetem Fogorvostudományi Kar Arc- Állcsont- Szájsebészeti és Fogászati Klinika Budapest
Outcome results
None listed