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Monitoring of neuromuscular blockade during general anaesthesia

Monitoring of neuromuscular blockade during general anaesthesia after reversal with neostigmine

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTR
Registry ID
EUCTR2019-000561-20-FI
Enrollment
120
Registered
2020-02-14
Start date
2020-02-28
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

We are studying reappearence of nondepolarizing neuromuscular block after it has been antagonized with a combination of neostigmine and glycopyrrolate. We are trying to find the incidence of the phenomenon.

Interventions

Trade Name: Glycostigmin Product Name: Glycostigmin Pharmaceutical Form: Injection

Sponsors

Tampere University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: AGE 18-65 years ASA risk class 1-2 Elective surgery reguiring general anaesthesia with estimated duration over 45 min. Body Mass Index (BMI) =65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Disease of central nervous system Previous injury of central nervous system Disease affecting peripheral nervous system, or medication affecting peripheral nervous system

Design outcomes

Primary

MeasureTime frame
Main Objective: To find the incidence of reappearance of nondepolarizing neuromuscular block after reversal with neostigmine.;Secondary Objective: Possible side-effects;Primary end point(s): Incidence of reappearence of nondepolarizing neuromuscular block after reversal with neostigmine.;Timepoint(s) of evaluation of this end point: Lenght of postanaesthesia care

Secondary

MeasureTime frame
Secondary end point(s): none;Timepoint(s) of evaluation of this end point: none

Countries

Finland

Contacts

Public ContactTampere University Hospital

Tampere University Hospital

3583311611

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026