To compare the response of treatment with platelet rich plasma or saline solution injections in patients with shoulder pain.

Value of ultrasound-guided treatment with Platelet Rich Plasma or high volume injection in the rotator cuff tendon: Prospective randomized clinical trial. EudraCT number 2018-003709-25 - PRPVol

Status

Not yet recruiting

Phases

Phase 3

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2018-003709-25-ES

Enrollment

Registered

2019-04-12

Start date

2019-06-11

Completion date

Unknown

Last updated

2019-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shoulder pain due to rotator cuff tendinopathy or partial tears of the supraspinatus tendon

Interventions

Trade Name: Platelet Rich Plasma Product Name: Platelet Rich Plasma Product Code: PRP Pharmaceutical Form: Blood fraction modifier INN o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Shoulder pain due to tendinopathy or partial tear of the supraspinatus tendon for more than 3 months. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 30 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 30

Exclusion criteria

Exclusion criteria: - Pregnancy. - Cutaneous infection in the area of the puncture. - Hematological disease. - History of bleeding. - Active systemic infection (HIV, HCV, Sepsis). - Active neoplastic disease.

Design outcomes

Primary

Measure	Time frame
Primary end point(s): -Pain (VAS) -Function (Quick test Dash) ; Timepoint(s) of evaluation of this end point: 1st visit 1.5 months. 3 months 6 months ;Main Objective: To evaluate the shoulder pain after treatment with ultrasound guided injection of Platelet rich plasma or High volumen injection in patients with shoulder pain due to tendinopathy or partial tears of the supraspinatus tendon;Secondary Objective: To evaluate the shoulder function after treatment with ultrasound guided injection of Platelet rich plasma or High volumen injection in patients with shoulder pain due to tendinopathy or partial tears of the supraspinatus tendon	—

Measure

Time frame

Primary end point(s): -Pain (VAS) -Function (Quick test Dash) ; Timepoint(s) of evaluation of this end point: 1st visit 1.5 months. 3 months 6 months ;Main Objective: To evaluate the shoulder pain after treatment with ultrasound guided injection of Platelet rich plasma or High volumen injection in patients with shoulder pain due to tendinopathy or partial tears of the supraspinatus tendon;Secondary Objective: To evaluate the shoulder function after treatment with ultrasound guided injection of Platelet rich plasma or High volumen injection in patients with shoulder pain due to tendinopathy or partial tears of the supraspinatus tendon

—

Secondary

Measure	Time frame
Secondary end point(s): Cost-effectiveness analysis of treatment with PRP versus high volumen injection .; Timepoint(s) of evaluation of this end point: 1st visit 1.5 months. 3 months 6 months	—

Countries

Spain

Contacts

Public ContactSecretaría Radiología

Hospital Son Llatzer

Españ0034678556372

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026