Hypotension during general anaesthesia or central blockades
Conditions
Interventions
Trade Name: Noradrenalin Abcur, Noradrenalin Hospira
Pharmaceutical Form: Concentrate for solution for infusion
Sponsors
Södersjukhuset
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 18 years or above who undergo general anaesthesia or central blockades in the operation theater with hypotension and need of vasopressor support can be included. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 500 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 500
Exclusion criteria
Exclusion criteria: Lack of consent. The patient has a central venous catheter in place.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To study side effects of peripheral administration of norepinephrine. ;Secondary Objective: Secondary objective is to study if the localisation of the peripheral venous catheter, the duration of the infusion or comorbidity are associated with higher complication rate. ;Primary end point(s): Percentage of adverse events and serious adverse events. We will study inadverent subcutaneous infusion, white colouring of the skin and hypertension (systolic blood pressure>220 mmHg) and skin necrosis;Timepoint(s) of evaluation of this end point: During the study period, maximum length 72 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Secondary aims are to evaluate if comorbidity, the localisation of the peripheral venous catheter or the duration of infusion is associated with higher incidence of complications. ;Timepoint(s) of evaluation of this end point: During the study period, maximum 72hours. | — |
Countries
Sweden
Contacts
Public ContactMaria Cronhjort
Södersjukhuset
Outcome results
None listed