postoperative effect of optimal pain management supplemented with a single dose of adrenocortical hormon in the first week after insertion of a knee prosthesis

postoperative effect of optimal multimodal pain management supplemented with systemic single dose of Dexamethason in the first week after UKA. Low dose (8mg) or mean dose

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2017-003003-22-DK

Enrollment

Registered

2017-10-10

Start date

2017-11-27

Completion date

Unknown

Last updated

2020-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis MedDRA version: 20.0 Level: LLT Classification code 10031165 Term: Osteoarthritis knee System Organ Class: 100000004859

Interventions

Trade Name: Dexametasone Product Name: Dexamethasone "KRKA" injektionsvæske, opløsning 4mg/ml Product Code: 29721 Pharmaceutical Form: Infusion INN or Proposed INN: DEXAMETHASONE DIPROPIONATE CAS Numb

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients =65 years) yes F.1.3.1 Number of subjects for this age range 35

Exclusion criteria

Exclusion criteria: Fertil women, daily use of opioids, NSAID or glucocorticoid, allergi to medicin used in the trial,alcohol abuse, cognictive dysfunction, severe kidney or hesrt disease, language barrier, operation in generel anaesthesia

Design outcomes

Primary

Measure	Time frame
Main Objective: Pain management i the first week after UKA;Secondary Objective: opiod use in the first week after UKA;Primary end point(s): knee pain, opioid use, knee swelling, PONV in the first week after UKA;Timepoint(s) of evaluation of this end point: one week after UKA	—

Secondary

Measure	Time frame
Secondary end point(s): wound complications in the first week after UKA;Timepoint(s) of evaluation of this end point: one week after UKA	—

Countries

Denmark

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026