Antimicrobial therapy in the surgical treatment of peri-implantitis

Adjunctive systemic antimicrobial therapy in the surgical treatment of peri-implantitis. A prospective randomized clinical study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2017-002532-16-BE

Enrollment

Registered

2017-08-07

Start date

2017-12-05

Completion date

Unknown

Last updated

2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To treat patients with chronic infection of dental implants. One group with antibiotics and one group without.

Interventions

Trade Name: Amoxicilline Product Name: Clamoxyl Pharmaceutical Form: Pillules Trade Name: Metronidazole Product Name: Flagyl Pharmaceutical Form: Pillules

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - one or more bleeding lesions in patients with chronic infection of dental implants. - Dutch Periodontal Screening Index from 0 to 2 - Full Mouth Plaque Score inferior or equal to 25% Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 20 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range 10

Exclusion criteria

Exclusion criteria: - smokers - pregnant and nursing women - patients with another parodontal disease excepted chronic infection of dental implants - systemic inflammatory disease (only based with clinical examination) - antibiotic in the previous 3 months

Design outcomes

Primary

Measure	Time frame
Main Objective: To evaluate the influence of the administration of antibiotics on the surgical treatment for chronic infection of dental implants.;Secondary Objective: Not applicable;Primary end point(s): - Measurement of dental plaque, gingival index, suppuration of sondage, depth of sondage, gingival recession.;Timepoint(s) of evaluation of this end point: The measurements will be done at first month, at 3 month and at 6 month	—

Measure

Time frame

Main Objective: To evaluate the influence of the administration of antibiotics on the surgical treatment for chronic infection of dental implants.;Secondary Objective: Not applicable;Primary end point(s): - Measurement of dental plaque, gingival index, suppuration of sondage, depth of sondage, gingival recession.;Timepoint(s) of evaluation of this end point: The measurements will be done at first month, at 3 month and at 6 month

—

Secondary

Measure	Time frame
Secondary end point(s): not applicable;Timepoint(s) of evaluation of this end point: not applicable	—

Countries

Belgium

Contacts

Public ContactDorian Gaudy

Cliniques Universitaires Saint-Luc

dorian.gaudy@uclouvain.be0032027645719

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026