Quadratus Lumborum Block, analgesic method for postoperative pain therapy after nephrectomy

Quadratus Lumborum Block (QLB): An effect on postoperative pain therapy and recovery after laparoscopic nephrectomy - QLB after laparoscopic nephrectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2017-002254-37-FI

Enrollment

Registered

2017-09-01

Start date

2017-10-18

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney cancer under laparoscopic radical nephrectomy as a curative therapy MedDRA version: 20.0 Level: LLT Classification code 10023400 Term: Kidney cancer System Organ Class: 100000056053

Interventions

Trade Name: Oradexon 5 mg/ml Product Name: Oradexon Pharmaceutical Form: Solution for solution for injection Other descriptive name: DEXAMETHASONE SODIUM PHOSPHATE Pharmaceutical form of the placebo:

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with kidney cancer under laparoscopic nephrectomy as a curative therapy. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 30 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 60

Exclusion criteria

Exclusion criteria: Age under 18 years, complicated diabetes mellitus type I, lack of finnish language skill and/or co-operation, chronic pain, hepatic insufficiency or other contraindication for paracetamol, steroid medication in regular use, contraindication for oxycodone.

Design outcomes

Primary

Measure	Time frame
Main Objective: Efficacy of Quadratus Lumborum Block for postoperative pain therapy and recovery after laparoscopic radical nephrectomy.;Secondary Objective: Prolonged postoperative pain after laparoscopic radical nephrectomy;Primary end point(s): Cumulative opiate consumption postoperatively;Timepoint(s) of evaluation of this end point: 24 hours after Quadratus Lumborum block placement.	—

Secondary

Measure	Time frame
Secondary end point(s): Postoperative analgesic consumption, nausea and vomiting, mobilisation, ileus, other complications, other recovery, length of hospital stay, long term quality of life and prolonged pain;Timepoint(s) of evaluation of this end point: Maximum 72 hours, queries at 2month, 6month, 12month postoperatively	—

Countries

Finland

Contacts

Public ContactMaija-Liisa Kalliomäki

Tampere University Hospital

maija-liisa.kalliomaki@pshp.fi+358331169424

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026