Improving pain management after hand assisted laparoscopic surgery for kidney cancer

Ultrasoundguided Transmuscular Quadratus Lumborum(TQL) block for hand assisted laparoscopic nephrectomy - a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2017-002130-23-DK

Enrollment

Registered

2017-06-01

Start date

2017-07-28

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The postoperative pain after Hand assisted lap.nephrectomy operation.Our one year retrospective study of patients with Kidney cancer treated with Hand assisted lap.nephrectomy revealed that, 71% of all patients undergoing Hand assisted lap.nephrectomy operation had a NRS score 3-10, and they needed substantial amounts of opioids to alleviate the postoperative pain

Interventions

Trade Name: Ropivacain Pharmaceutical Form: Injection INN or Proposed INN: Ropivacain Other descriptive name: ROPIVACAINE HYDROCHLORIDE

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Performing elective hand.ass.lap. nephrectomu in general anesthesia, Received written and oralinformation about the study and sign the informed consent form of participating the study, ASA 1-3 Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 20 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 30

Exclusion criteria

Exclusion criteria: Unabel to understand Danish in written or spoken language, Unable to Cooperato to the procedure, daily use of opioidsKnown abouse of alcohol ore medicationDiffcuilities in visualizing nerve ore muscle structure necessary for performing the block

Design outcomes

Primary

Measure	Time frame
Main Objective: To demonstrate whether a unilateral USG TQL block can reduce opioid consumption with clinical significance in kidney cancer patients operated with hand ass. lap nephrectomy;Secondary Objective: not applicable;Primary end point(s): total doses of Opioid during the first 12 postoperative hours;Timepoint(s) of evaluation of this end point: 12 hours	—

Secondary

Measure	Time frame
Secondary end point(s): Total dose of opioids during the first 24 hours,NRS (0-10) pain scores at rest, time in recovery, time to ambulation, total Length of stay. Adverse effects of oipiods;Timepoint(s) of evaluation of this end point: 24 hours	—

Countries

Denmark

Contacts

Public ContactJens Børglum

Dept of Anesth. Zealand university hospital Roskilde

jedn@regionsjaelland.dk4530700112

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026