Influence of epidural analgesia on opioid consumption and patients recovery after bowel surgery.

Influence of epidural analgesia on opioid consumption and patients recovery after laparoskopic colorectal surgery. - EPRAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2017-001714-29-FI

Enrollment

160

Registered

2017-06-14

Start date

2017-08-09

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Compare epidural and conventional pain treatment after laparoskopic colorectal surgery.

Interventions

Trade Name: Ropivacain Orion 2 mg/ml inf. liuos Product Name: Ropivacain Orion 2 mg/ml inf. liuos Product Code: N01BB09 Pharmaceutical Form: Solution for injection/infusion INN or Proposed INN: ROPI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Laparoskopic colorectal surgery, informed consent given. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 90 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 70

Exclusion criteria

Exclusion criteria: Severe renal, hepatic insufficiency, severe COPD, cancer T4, hematological disease, preoperative use of opioids, coagulation disturbances or any impossibility to put epidural catheter, over 50% risk of surgery conversion.

Design outcomes

Primary

Measure	Time frame
Main Objective: Primary outcome is the opioid consumption 48h postoperatively.;Secondary Objective: Secondary outcomes: pain intensity, initiation of the bowel action, intraoperative fluid balance, postoperative complications, ward-stay time. Additionally, we will compare the efficacy of pain treatments in two subgroups: left- and right hemicolonectomy.;Primary end point(s): Primary outcome is the opioid consumption 48h postoperatively.;Timepoint(s) of evaluation of this end point: 48h and 3 month after surgery.	—

Measure

Time frame

Main Objective: Primary outcome is the opioid consumption 48h postoperatively.;Secondary Objective: Secondary outcomes: pain intensity, initiation of the bowel action, intraoperative fluid balance, postoperative complications, ward-stay time. Additionally, we will compare the efficacy of pain treatments in two subgroups: left- and right hemicolonectomy.;Primary end point(s): Primary outcome is the opioid consumption 48h postoperatively.;Timepoint(s) of evaluation of this end point: 48h and 3 month after surgery.

—

Secondary

Measure	Time frame
Secondary end point(s): Secondary outcomes: pain intensity, initiation of the bowel action, intraoperative fluid balance, postoperative complications, ward-stay time. Additionally, we will compare the efficacy of pain treatments in two subgroups: left- and right hemicolonectomy.;Timepoint(s) of evaluation of this end point: 3 month	—

Countries

Finland

Contacts

Public ContactAlexey Schramko

Helsinki University hospital

aschramko@hotmail.com+358504270610

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026